No Wasted Lives supports a portfolio of operational research to build the evidence around ways to improve the quality, coverage, and cost-effectiveness of programmes for acute malnutrition across the world. These include:

Simplified protocols for the treatment of acute malnutrition

  • ComPAS: Testing combined protocols for the treatment of MAM/SAM, South Sudan and Kenya.

  • ComPAS Follow up: Long-term risk and benefits for children treated for moderate acute malnutrition with ready-to-use therapeutic food, Kenya.

  • Hi-MAM Study: Treatment of High-Risk Moderate Acute Malnutrition using expanded admission criteria, Sierra Leone.

  • MANGO: Testing reduced dosage for treatment, Burkina Faso.

  • OPTIMA DRC: OPTImizing acute malnutrition treatment in children 6 to 59 months.  A community-based randomized nutrition trial of a simplified treatment protocol, DRC.

Models for detection and treatment in the community

  • C-Project Mali: Testing the integration of SAM treatment into the iCCM package, Mali.

  • C-Project Pakistan: Testing the integration of SAM treatment into the iCCM package, Pakistan.

  • CeaSurge: IMAM Surge Approach and Family MUAC: improving early detection, referral and prevention of malnutrition in the community, Kenya.

Innovative approaches to diagnosis of acute malnutrition

  • OptiDiag: Biomedical Investigations for Optimized Diagnosis and Monitoring of Severe Acute Malnutrition (SAM): Elucidating the heterogeneous diagnosis of SAM by current anthropometric criteria and moving beyond.

Understanding treatment success and non-respondance

  • The PROMIS Study: Working out why MAM and SAM treatment isn’t always successful, Mali and Burkina Faso.

For more information about research projects related to acute malnutrition from organisations around the world visit the Ongoing Research interactive map on