Building the evidence


No Wasted Lives supports a portfolio of operational research to build the evidence around ways to improve the quality, coverage, and cost-effectiveness of programmes for acute malnutrition across the world. These include:

Simplified protocols for the treatment of wasting

  • ComPAS: Testing combined protocols for the treatment of moderate and severe acute malnutrition, South Sudan and Kenya. Read more.

  • ComPAS Follow up: Long-term risk and benefits for children treated for moderate acute malnutrition with ready-to-use therapeutic food, Kenya. Read more.

  • Hi-MAM Study: Treatment of High-Risk Moderate Acute Malnutrition using expanded admission criteria, Sierra Leone. Read more.

  • MANGO: Testing reduced dosage for treatment, Burkina Faso. Read more.

  • OPTIMA DRC: OPTImising acute malnutrition treatment in children 6 to 59 months. A community-based randomised nutrition trial of a simplified treatment protocol, DRC. Read more.

Models for detection and treatment in the community

  • C-Project Mali: Testing the integration of treatment for severe acute malnutrition into the Integrated Community Case Management package, Mali. Read more.

  • C-Project Pakistan: Testing the integration of severe acute malnutrition treatment into the Integrated Community Case Management package, Pakistan. Read more.

  • CeaSurge: Operations research on mothers’ use of MUAC screening to improve early detection, referral and prevention of malnutrition among children under the age of five in North Horr pastoralist communities, Kenya. Read more.

Innovative approaches to diagnosis of acute malnutrition

  • OptiDiag: Biomedical Investigations for Optimised Diagnosis and Monitoring of Severe Acute Malnutrition (SAM): Elucidating the heterogeneous diagnosis of SAM by current anthropometric criteria and moving beyond. Read more.

Understanding treatment success and non-respondance

For more information about research projects related to acute malnutrition from organisations around the world visit the Ongoing Research interactive map on